Yaddle1 is a potent agonist of the mechano-activated ion channel Piezo1, exhibiting a half-maximal effective concentration (MEC50) of 0.40 μM. This compound effectively promotes Ca2+ influx in T cells, leading to significant T cell activation. Yaddle1 serves as a valuable tool in research applications focused on vaccine adjuvants and the modulation of immune responses.
Yaddle1 is a potent agonist of the mechano-activated ion channel Piezo1, exhibiting a half-maximal effective concentration (MEC50) of 0.40 μM. This compound effectively promotes Ca2+ influx in T cells, leading to significant T cell activation. Yaddle1 serves as a valuable tool in research applications focused on vaccine adjuvants and the modulation of immune responses.
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