Fig. 1 · Structure

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YC-001

Rod Opsin Inverse Agonist and Antagonist

YC-001 is an inverse agonist and antagonist of rod opsin, designed to reversibly bind and stabilize the rod opsin structure. This compound demonstrates protective effects against bright light-induced retinal degeneration in murine models. YC-001 holds potential for research applications focused on retinal degeneration and the underlying mechanisms of photoreceptor cell protection.

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Specifications

Manufacturer Adooq Bioscience
Actions Inverse Agonist
CAS Number 748778-73-6
Applications Rod Opsin Inverse Agonist and Antagonist
Formula C12H7ClO2S2
Molecular Weight 282.77
SMILES
O=C1OCC(C2=CC=C(Cl)S2)=C1C3=CC=CS3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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