Fig. 1 · Structure
Documents & Downloads
yGsy2p-IN-1
Glycogen Synthase Inhibitor
yGsy2p-IN-1 is a potent inhibitor of yeast glycogen synthase 2 (yGsy2p) and functions as a competitive inhibitor of human glycogen synthase 1 (hGYS1). With an IC50 of 2.75 μM and a Ki of 1.31 μM for wild-type hGYS1, this pyrazole compound demonstrates significant efficacy in modulating glycogen synthesis. It is particularly useful in the study of glycogen storage diseases (GSDs), providing insights into molecular mechanisms and potential therapeutic approaches.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2415003-97-1 |
| Applications | Glycogen Synthase Inhibitor |
| Formula | C16H11F3N2O4 |
| Molecular Weight | 352.26 |
| SMILES | OC1=CC=C(C2=NNC(C(F)(F)F)=C2C3=CC=C(O)C=C3)C(O)=C1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.