Fig. 1 · Structure
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YHS-12
Cationic Lipid
YHS-12 is an ionizable cationic lipid that plays a crucial role in the formulation of lipid nanoparticles (LNPs) for the effective delivery of siRNA and mRNA. Its ability to encapsulate nucleic acids enhances gene silencing and gene expression studies, making it a valuable tool in nucleic acid therapeutics and vaccine development. YHS-12 facilitates efficient cellular uptake and endosomal release, thus enabling robust mRNA and siRNA delivery in various research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2959463-68-2 |
| Applications | Cationic Lipid |
| Formula | C56H112N4O2 |
| Molecular Weight | 873.51 |
| SMILES | CCCCCCCCCCCCN(CCCCCCCCCCCC)CCNC(/C=C/C(NCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.