YKL-05-099

Name: YKL-05-099
Brand: Adooq Bioscience
SKU: A20553
Rating: 5 (288 reviews)

Catalog No.: A20553

SIK inhibitor

YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM).

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Grouped product items
Size	Price	Stock
1mg	$60.00	In stock
5mg	$115.00	In stock
10mg	$180.00	In stock
25mg	$320.00	In stock
50mg	$480.00	In stock
100mg	$680.00	In stock
*10mM 1mL in DMSO**	$155.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM).

Product Information

Catalog Num	A20553
Formula	C32H34ClN7O3
Molecular Weight	600.11
CAS Number	1936529-65-5
SMILES	O=C1N(C2=NC=C(OC)C=C2)C3=NC(NC4=CC=C(C5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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