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YM-17E hydrochloride

ACAT Inhibitor

YM-17E hydrochloride is a potent inhibitor of acyl CoA:cholesterol acyltransferase (ACAT), demonstrating an IC50 of 44 nM. This compound exhibits significant hypocholesterolemic effects, making it valuable for research in cholesterol metabolism and cardiovascular disease. Its application in studies on lipid regulation may advance understanding of lipid-related disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	124884-99-7
Applications	ACAT Inhibitor
Formula	C₄₀H₅₈Cl₂N₆O₂
Molecular Weight	725.83
SMILES	O=C(NC1=CC=C(N(C)C)C=C1)N(CC2=CC=CC(CN(C3CCCCCC3)C(NC4=CC=C(N(C)C)C=C4)=O)=C2)C5CCCCCC5.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.