Fig. 1 · Structure
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YM-254890
Gαq/11 Selective Inhibitor
YM-254890 is a selective inhibitor of Gαq/11 proteins, derived from Chromobacterium sp. This compound effectively inhibits platelet aggregation induced by ADP by targeting the P2Y1 signal transduction pathway, demonstrating an IC50 value of less than 0.6 μM. Its specificity for Gαq/11 makes it a valuable tool for investigating signaling pathways and biological processes associated with these G protein subtypes in research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 568580-02-9 |
| Applications | Gαq/11 Selective Inhibitor |
| Formula | C46H69N7O15 |
| Molecular Weight | 960.08 |
| SMILES | CN([C@@H](C)C(N[C@@H]([C@H](OC([C@@H](NC(C)=O)[C@@H](C(C)C)O)=O)C(C)C)C(N(C)[C@@H]([C@H](OC)C)C(O[C@@H]1C)=O)=O)=O)C([C@H](C)NC(C(N(C([C@@H](CC2=CC=CC=C2)OC([C@H]1NC(C)=O)=O)=O)C)=C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.