Fig. 1 · Structure
Documents & Downloads
YM-31636 free base
5-HT3 Receptor Agonist
YM-31636 free base is a potent and selective agonist of the 5-HT3 receptor, exhibiting a Ki value of 0.2 nM. This compound effectively induces contraction in isolated guinea pig distal colon, suggesting its role in gastrointestinal motility. Additionally, YM-31636 free base demonstrates tachycardia through a relative intrinsic activity of approximately 0.23 in isolated guinea pig right atrium, indicating potential applications in research focusing on constipation and related gastrointestinal disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 159081-22-8 |
| Applications | 5-HT3 Receptor Agonist |
| Formula | C14H11N3S |
| Molecular Weight | 253.32 |
| SMILES | C1(CC2=NC3=C(S2)CC4=C3C=CC=C4)=CN=CN1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.