Fig. 1 · Structure
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YM-358 hydrate potassium
AT1 Antagonist
YM-358 hydrate potassium is an orally active antagonist of the angiotensin II type 1 (AT1) receptor. This compound demonstrates the potential to reduce cardiac volume overload, making it a valuable tool for investigating cardiovascular diseases, particularly hypertension. Researchers can utilize YM-358 hydrate potassium to explore therapeutic avenues in managing cardiovascular conditions associated with AT1 receptor activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 161800-08-4 |
| Applications | AT1 Antagonist |
| Formula | C22H24KN8O |
| Molecular Weight | 455.58 |
| SMILES | CCC1=CN(N2N=C(N=C21)CC)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5.[K].O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.