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YM116

Name: YM116
Brand: Adooq Bioscience
SKU: A69913
Availability: OutOfStock

Cat. No. A69913 CAS 183012-13-7

CYP17A1 Inhibitor

YM116 is a potent and orally active competitive inhibitor of CYP17A1, with a reported Ki of 0.38 nM. By specifically inhibiting the C17-20 lyase activity, YM116 effectively reduces the synthesis of adrenal androgens, leading to decreased serum testosterone levels and lower dehydroepiandrosterone sulfate concentrations. This compound is valuable for research applications involving androgen-related disorders and prostate health.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	183012-13-7
Applications	CYP17A1 Inhibitor
Formula	C₁₆H₁₃N₃
Molecular Weight	247.29
SMILES	C1(NC2=C3C=CC=C2)=C3C=CC(CC4=CN=CN4)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.