YM155 (Sepantronium Bromide)

Name: YM155 (Sepantronium Bromide)
SKU: A11002
Price: 25 USD
Rating: 5 (13 reviews)

Catalog No.: A11002

Survivin Inhibitor

Adooq's YM155 (Sepantronium Bromide) has been cited by 13 publications

YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock
2mg	$25.00	In stock
5mg	$35.00	In stock
10mg	$65.00	In stock
25mg	$145.00	In stock
50mg	$265.00	In stock
100mg	$395.00	In stock
500mg	$975.00	In stock
*10mM 1mL in DMSO**	$50.00	In stock
Bulk Size	Bulk Discount

Notify me when the price drops

Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Other Forms of YM155 (Sepantronium Bromide)

YM-155 HCl (Sepantronium HCl)

Adooq Products cited in reputable paper

Adooq's YM155 (Sepantronium Bromide) has been cited by 13 publications

Atieh Pourbagheri-Sigaroodi, .et al. , Iran J Allergy Asthma Immunol, 2024, 23(6):699-726

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Ali Nasrollahzadeh, .et al. , Biochim Biophys Acta Mol Cell Res, 2021, Jun 26;1868(10):119087 PMID: 34182011

Chia-Hui Huang, .et al. , Toxicol Appl Pharmacol, 2020, Apr 17;397:115013 PMID: 32305283

Turner TH, .et al. , Sci Rep, 2020, Jan 30;10(1):1493 PMID: 32001757

Chiou JT, .et al. , Toxicol Appl Pharmacol, 2019, Dec 16;387:114857 PMID: 31837377

Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259

Momeny M, .et al. , Cell Oncol (Dordr), 2019, Apr 25 PMID: 31025257

Yamamoto M, .et al. , Anticancer Res, 2019, Feb;39(2):609-617 PMID: 30711936

V??zquez-Mellado MJ, .et al. , Oncol Rep, 2018, Nov 27 PMID: 30483799

MASAHIRO YAMAMOTO, .et al. , Anticancer Res, 2018, Dec 38 (12) 6699-6706 PMID: 30504379

Ahn MR, .et al. , Drug Discov Ther, 2017, 11(6):300-306 PMID: 29332887

MASAYA MINODA, .et al. , Int J Oncol, 2015, Sep; 47(3): 891-899 PMID: 26166250

Biological Activity

Discription

YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.

Targets

Target	Value

Product Information

Catalog Num	A11002
Formula	C20H19BrN4O3
Molecular Weight	443.3
CAS Number	781661-94-7
SMILES	CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	52 mg/mL (117.3 mM)
	Water	85 mg/mL (191.75 mM)
	Ethanol	6 mg/mL (13.53 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.56 mL	112.79 mL	225.58 mL
0.5 mM	4.51 mL	22.56 mL	45.12 mL
1 mM	2.26 mL	11.28 mL	22.56 mL
5 mM	0.45 mL	2.26 mL	4.51 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂