YM155 (Sepantronium Bromide)

Catalog No.: A11002

Survivin Inhibitor

YM155 (Sepantronium Bromide) Chemical Structure

CAS NO. 781661-94-7

YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $32.00

10 mg

Regular Price: $70.00

Special Price $56.00

25 mg

Regular Price: $150.00

Special Price $120.00

100 mg

Regular Price: $400.00

Special Price $320.00

10mM * 1mL in DMSO
$50.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.
Targets
Survivin (HeLa-SURP-luc, CHO-SV40-luc cells)
0.54 nM
In vitro (25°C) DMSO 55 mg/mL (124.07 mM)
Water 89 mg/mL (200.77 mM)
Ethanol 6 mg/mL (13.53 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.56 mL 112.79 mL 225.58 mL
0.5 mM 4.51 mL 22.56 mL 45.12 mL
1 mM 2.26 mL 11.28 mL 22.56 mL
5 mM 0.45 mL 2.26 mL 4.51 mL

*The above data is based on the productmolecular weight 443.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11002
Actions Inhibitor
M. Wt 443.3
Formula C20H19BrN4O3
Solubility DMSO>89mg/mL Water>89mg/mL Ethanol>24mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 781661-94-7
SMILES CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]

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