Fig. 1 · Structure
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YM758
If Channel Inhibitor
YM758 is a selective inhibitor of the "funny" If current channels, known to regulate the pacemaker potential in cardiac tissues. This compound exhibits significant activity in modulating heart rate and rhythm through inhibition of hyperpolarization-activated cyclic nucleotide-gated channels. It is commonly used in cardiovascular research to investigate mechanisms of action related to heart function and potential therapeutic interventions for arrhythmias.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 312752-85-5 |
| Applications | If Channel Inhibitor |
| Formula | C26H32FN3O4 |
| Molecular Weight | 469.55 |
| SMILES | O=C([C@H]1CN(CCC1)CCNC(C2=CC=C(F)C=C2)=O)N3CC4=CC(OC)=C(OC)C=C4CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.