Fig. 1 · Structure
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YOK-1304
p62 Ligand
YOK-1304 is a selective ligand for the p62 ZZ domain, promoting p62-dependent selective macroautophagy. This compound plays a crucial role in the activation of autophagic processes, making it valuable for research involving selective autophagy pathways. Additionally, YOK-1304 can be utilized in the design of AUTOTAC (autophagy-targeting chimeras) for targeted therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2409960-03-6 |
| Applications | p62 Ligand |
| Formula | C28H35NO4 |
| Molecular Weight | 449.58 |
| SMILES | CC(C)NC[C@@H](O)COC1=CC(OCCCC2=CC=CC=C2)=C(OCC3=CC=CC=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.