Fig. 1 · Structure
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YT-8-8
p62 Ligand
YT-8-8 functions as a ligand for the p62-ZZ domain, promoting p62-dependent selective macroautophagy. This compound is valuable for research applications focused on autophagy modulation and the development of AUTOTAC (Autophagy Tethering Compounds) strategies. Its potential to influence autophagic processes makes YT-8-8 an important tool for studying cellular degradation pathways and their implications in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 892572-23-5 |
| Applications | p62 Ligand |
| Formula | C18H23FN2O2 |
| Molecular Weight | 318.39 |
| SMILES | OCCNCCNCC1=CC(OCC2=CC=C(F)C=C2)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.