Fig. 1 · Structure
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YTK-105
p62 Ligand
YTK-105 is a ligand specific to the p62-ZZ domain, effectively activating p62-dependent selective macroautophagy. This compound is valuable for research applications in autophagy modulation and the design of AUTOTAC molecules. Its ability to engage the p62 pathway makes it a crucial tool for investigating cellular degradation processes and the role of autophagy in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 774192-20-0 |
| Applications | p62 Ligand |
| Formula | C16H19NO2 |
| Molecular Weight | 257.33 |
| SMILES | OCCNCC1=CC=CC(OCC2=CC=CC=C2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.