Fig. 1 · Structure
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YW2065
Axin-1 Stabilizer
YW2065 is an Axin-1 stabilizer that functions by enhancing the stability of the Axin-1 protein, which plays a crucial role in regulating the proteasomal degradation of β-catenin. This compound demonstrates significant anti-colorectal cancer effects through the dual mechanisms of inhibiting Wnt/β-catenin signaling and activating AMP-activated protein kinase (AMPK). YW2065 is a valuable tool for research focused on cancer biology and the modulation of signaling pathways involved in tumor progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Stabilizer |
| CAS Number | 2131223-85-1 |
| Applications | Axin-1 Stabilizer |
| Formula | C20H15BrN4O |
| Molecular Weight | 407.26 |
| SMILES | O=C(C1=C(C)N(C2=CC=CC=C2Br)N=C1)NC3=NC4=CC=CC=C4C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.