Fig. 1 · Structure
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YZ51
Ribonucleotide Reductase Inhibitor
YZ51 is a potent ribonucleotide reductase (RR) inhibitor exhibiting enhanced anti-HBV activity compared to its parent compound Osalmid. With an IC50 value of 0.6 μM against recombinant RR activity and 23.7 μM against HepG2.2.15 cell-derived RR activity, YZ51 serves as a valuable tool for investigating the role of RR in viral replication dynamics. This compound can aid research in virology and therapeutic approaches to hepatitis B virus infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1835652-66-8 |
| Applications | Ribonucleotide Reductase Inhibitor |
| Formula | C16H14FNO2 |
| Molecular Weight | 271.29 |
| SMILES | O=C(C1=CC=C(C=C1F)C2CC2)NC3=CC=C(C=C3)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.