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Z-FK-ck

Gingipain-K Inhibitor

Z-FK-ck is a potent and selective inhibitor of gingipain-K, a key enzyme involved in the virulence of certain pathogenic bacteria. This compound has been shown to extend plasma thrombin time (TT) in a dose- and time-dependent manner, suggesting its potential utility in studying coagulation processes and bacterial infections. Its specificity makes Z-FK-ck valuable for research applications focused on understanding the role of gingipains in disease and developing therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	118253-05-7
Applications	Gingipain-K Inhibitor
Formula	C₃₄H₄₁N₃O₆
Molecular Weight	587.71
Synonyms	Z-Phe-Lys-2,4,6-Trimethylbenzoyloxy-methylketone
SMILES	C(OCC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(OCC2=CC=CC=C2)=O)=O)CCCCN)=O)(=O)C3=C(C)C=C(C)C=C3C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.