Fig. 1 · Structure
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Z-GGF-CMK
Protease Inhibitor
Z-GGF-CMK is a potent protease inhibitor that targets ClpP1P2 and the proteasome. This compound exhibits notable cytotoxicity in HepG2 cells, demonstrating an effective CC50 value of 125 μM. Z-GGF-CMK is valuable for research into cellular regulation, proteolytic pathways, and anticancer studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 35172-59-9 |
| Applications | Protease Inhibitor |
| Formula | C22H24ClN3O5 |
| Molecular Weight | 445.90 |
| SMILES | [C@@H](CC1=CC=CC=C1)(NC(CNC(CNC(OCC2=CC=CC=C2)=O)=O)=O)C(CCl)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.