Z-Gly-Gly-Phe-OH

Catalog No.: A68475
Active Compound
Z-Gly-Gly-Phe-OH is a substrate for serine proteases such as pepsin and thermolysin, exhibiting an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. This compound effectively participates in enzyme-catalyzed condensation reactions to form peptide bonds with amine components, including H-Leu-NHPh. Z-Gly-Gly-Phe-OH serves as a valuable intermediate in peptide synthesis, making it essential for various biochemical research applications.
Grouped product items
Size Price Stock Qty
100mg
$60.00
In stock
250mg
$95.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZ-Gly-Gly-Phe-OH is a substrate for serine proteases such as pepsin and thermolysin, exhibiting an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. This compound effectively participates in enzyme-catalyzed condensation reactions to form peptide bonds with amine components, including H-Leu-NHPh. Z-Gly-Gly-Phe-OH serves as a valuable intermediate in peptide synthesis, making it essential for various biochemical research applications.
Product Information
Catalog NumA68475
FormulaC21H23N3O6
Molecular Weight413.42
CAS Number13171-93-2
SMILESO=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(OCC2=CC=CC=C2)=O)=O)=O
Useful Calculator

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