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Z-NCTS

RNA Molecular Glue

Z-NCTS is an RNA molecular glue that targets the RNA mismatch binding site, specifically recognizing the 5’-r(XGG)-3’/5’-r(XGG)-3’ sequence, where X can be U or A. This compound facilitates the stabilization of RNA structures through its binding properties, making it a valuable tool for studying RNA interactions and dynamics. Z-NCTS can be utilized in various research applications, including RNA structure-function studies and the exploration of RNA-based therapeutics.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	1373391-77-5
Applications	RNA Molecular Glue
Formula	C₆₈H₇₀N₁₄O₈
Molecular Weight	1211.37
SMILES	CC1=NC2=C(C=C1)C=CC(NC(OCCCN(CCCOC(NC3=NC4=C(C=CC(C)=N4)C=C3)=O)CC(C=C5)=CC=C5/C=C\C(C=C6)=CC=C6CN(CCCOC(NC7=NC8=C(C=CC(C)=N8)C=C7)=O)CCCOC(NC9=NC%10=C(C=CC(C)=N%10)C=C9)=O)=O)=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.