Fig. 1 · Structure
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ζ-Stat trisodium
PKC-ζ Inhibitor
ζ-Stat trisodium is a selective inhibitor of protein kinase C zeta (PKC-ζ), exhibiting an IC50 of 5 μM. This compound effectively reduces the proliferation of melanoma cell lines and induces apoptotic cell death. Its antitumor activity in vitro supports its potential application in cancer research and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 31894-34-5 |
| Applications | PKC-ζ Inhibitor |
| Formula | C10H5Na3O10S3 |
| Molecular Weight | 450.31 |
| Synonyms | NSC37044 trisodium |
| SMILES | O=S(C1=C2C(O)=CC(S(=O)(O[Na])=O)=CC2=CC(S(=O)(O[Na])=O)=C1)(O[Na])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.