Fig. 1 · Structure
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Z-VDVA-(DL-Asp)-FMK
Z-VDVAD-FMK Derivative
Z-VDVA-(DL-Asp)-FMK is a derivative of Z-VDVAD-FMK, specifically designed as a selective inhibitor of caspase-2. This compound demonstrates significant capacities in modulating apoptotic pathways and is useful in the study of cell death processes. Its application extends to research involving neurodegenerative diseases, cancer biology, and other areas where caspase-2 activity plays a critical role.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1926163-61-2 |
| Applications | Z-VDVAD-FMK Derivative |
| Formula | C32H46FN5O11 |
| Molecular Weight | 695.73 |
| Synonyms | Z-VD(OMe)VAD(OMe)-(DL-Asp)-FMK |
| SMILES | COC(CC(C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(OC)=O)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.