Z3071585108 is a small molecule inhibitor of the LAG-3 D1 domain, exhibiting Kd values of 59.2 μM and 56.1 μM through MST-TRIC channel and spectral shift detection, respectively. This compound partially inhibits the interaction between LAG-3 and MHC class II molecules, with an EC₅₀ value of 42.9 μM. Z3071585108 is valuable for research on small molecule immunotherapies targeting the LAG-3 pathway, contributing to the understanding of immune modulation in various diseases.
Z3071585108 is a small molecule inhibitor of the LAG-3 D1 domain, exhibiting Kd values of 59.2 μM and 56.1 μM through MST-TRIC channel and spectral shift detection, respectively. This compound partially inhibits the interaction between LAG-3 and MHC class II molecules, with an EC₅₀ value of 42.9 μM. Z3071585108 is valuable for research on small molecule immunotherapies targeting the LAG-3 pathway, contributing to the understanding of immune modulation in various diseases.
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