Z433927330

Catalog No.: A18401

AQP7 inhibitor

Z433927330

Z433927330 Chemical Structure

CAS NO. 1005883-72-6

Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 ?M, ~0.7 ?M and ~1.1 ?M for mAQP7, mAQP3 and mAQP9, respectively.

Availability: In stock

Package Price Qty
5 mg
$300.00
10 mg
$500.00
50 mg
$1,500.00
100 mg
$2,400.00
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Biological Activity

Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 ?M, ~0.7 ?M and ~1.1 ?M for mAQP7, mAQP3 and mAQP9, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.44 mL 137.21 mL 274.42 mL
0.5 mM 5.49 mL 27.44 mL 54.88 mL
1 mM 2.74 mL 13.72 mL 27.44 mL
5 mM 0.55 mL 2.74 mL 5.49 mL

*The above data is based on the productmolecular weight 364.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18401
Actions Inhibitor
M. Wt 364.4
Formula C20H20N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1005883-72-6
Synonyms Z 433927330, Z-433927330
SMILES O=C(OCC)C1=CC=C(NC(NCC2=CC=C(N3N=CC=C3)C=C2)=O)C=C1

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