Fig. 1 · Structure

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Z52-L16

Ras Inhibitor

Z52-L16 is a Ras inhibitor that functions through the modulation of key signaling pathways involved in tumorigenesis. This drug-linker conjugate is specifically designed for antibody-drug conjugate (ADC) applications, facilitating targeted delivery in cancer research. Z52-L16 is particularly relevant for studies focused on pancreatic cancer, providing a valuable tool for investigating therapeutic strategies against Ras-driven malignancies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3077488-80-0
Applications Ras Inhibitor
Formula C130H196N14O45S
Molecular Weight 2707.08
SMILES
N#CC1(CNC(OCC2=CC=C(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)C(NC(CCNC([C@@H](NC(CCN4C(C=CC4=O)=O)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)=C2)=O)CCN(CC1)CC#CC5=C[C@@]([C@@]6=C7C8=CC(C9=CSC(C[C@H](NC([C@@H]%10[C@H]%11COC[C@@H]%10%11)=O)C(N%12N[C@H](C(OCC(C7)(C)C)=O)CCC%12)=O)=N9)=CC=C8N6CC)=C(N=C5)[C@@H](OC)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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