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Z6466608628

PPIL4 Molecular Glue Degrader

Z6466608628 is a selective PPIL4 molecular glue degrader, exhibiting an EC50 of 0.34 μM. PPIL4 plays a critical role in regulating the BACR spliceosome and is essential for brain angiogenesis. This compound is particularly valuable for research related to intracranial aneurysms (IA) and elucidating the molecular mechanisms of angiogenesis in the brain.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2869183-63-9
Applications	PPIL4 Molecular Glue Degrader
Formula	C₂₃H₂₄N₄O₃
Molecular Weight	404.46
SMILES	O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=CC=C3C4=CC=C(C=C4)N5CCNCC5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.