Zacopride is a potent orally active antagonist of the 5-HT3 receptor, with a Ki value of 0.38 nM, and an agonist of the 5-HT4 receptor, exhibiting a Ki of 373 nM. This compound demonstrates significant biological activities, including the regulation of gastrointestinal motility, modulation of cardiac function, and the provision of anxiolytic and antiemetic effects. Zacopride is primarily utilized in research focusing on gastrointestinal disorders, cardiovascular conditions, and psychiatric diseases such as anxiety.
Zacopride is a potent orally active antagonist of the 5-HT3 receptor, with a Ki value of 0.38 nM, and an agonist of the 5-HT4 receptor, exhibiting a Ki of 373 nM. This compound demonstrates significant biological activities, including the regulation of gastrointestinal motility, modulation of cardiac function, and the provision of anxiolytic and antiemetic effects. Zacopride is primarily utilized in research focusing on gastrointestinal disorders, cardiovascular conditions, and psychiatric diseases such as anxiety.
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