Fig. 1 · Structure
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Zalunfiban dihydrochloride
αIIbβ3 Antagonist
Zalunfiban dihydrochloride is a potent, selective antagonist of the platelet integrin αIIbβ3, exhibiting an IC50 of 45 nM. This compound is primarily utilized in research related to myocardial infarction (MI), providing insight into platelet aggregation and thrombus formation. Its selective inhibition of αIIbβ3 makes it a valuable tool for studying cardiovascular events and associated therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2815778-41-5 |
| Applications | αIIbβ3 Antagonist |
| Formula | C16H20Cl2N8O2S |
| Molecular Weight | 459.35 |
| Synonyms | RUC-4 dihydrochloride |
| SMILES | O=C(NC1=CC(C(S2)=NN(C2=NC(N3CCNCC3)=C4)C4=O)=CN=C1)CN.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.