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Zantrutide

Catalog No.: A60614
GIPR/GLP-1R Agonist
Zantrutide is an agonist of the glucagon, gastric inhibitory polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). It exhibits significant biological activity in the modulation of glucose metabolism and insulin secretion. This compound is valuable for research applications targeting metabolic diseases, particularly in the exploration of obesity and type 2 diabetes treatment strategies.
Zantrutide 3060140-36-2 GIPR/GLP-1R Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZantrutide is an agonist of the glucagon, gastric inhibitory polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). It exhibits significant biological activity in the modulation of glucose metabolism and insulin secretion. This compound is valuable for research applications targeting metabolic diseases, particularly in the exploration of obesity and type 2 diabetes treatment strategies.
Product Information
Catalog NumA60614
FormulaC236H352N56O72
Molecular Weight5125.65
CAS Number3060140-36-2
SequenceHis-{Aib}-His-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-{Lys(AEEA-AEEA-γGlu-C20 diacid)}-Tyr-Leu-Asp-cylco{Glu-Lys-Ala-Ala-Lys}-Asp-Phe-Val-Gln--Trp-Leu-Leu-Asp-Gln-His-Pro-Ser-Ser-Gly-Gln--Pro-Pro-Pro-Ser-NH2
Sequence shorteningH-{Aib}-HGTFTSDYS-{Lys(AEEA-AEEA-γGlu-C20 diacid)}-YLD-cylco{EKAAK}DFVQWLLDQHPSSGQPPPS-NH2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > GLP-1 receptors