ZCL279 is a small molecule modulator that selectively inhibits the interaction between Cdc42 and intersectin (ITSN). At lower concentrations (<10 μM), ZCL279 stimulates Cdc42 activation, while at higher concentrations, it exerts a significant inhibitory effect on Cdc42 activity. This dual functionality makes ZCL279 a valuable tool for studying the role of Cdc42 in cellular signaling pathways and its implications in various biological processes and diseases.
ZCL279 is a small molecule modulator that selectively inhibits the interaction between Cdc42 and intersectin (ITSN). At lower concentrations (<10 μM), ZCL279 stimulates Cdc42 activation, while at higher concentrations, it exerts a significant inhibitory effect on Cdc42 activity. This dual functionality makes ZCL279 a valuable tool for studying the role of Cdc42 in cellular signaling pathways and its implications in various biological processes and diseases.
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