Fig. 1 · Structure
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ZDLD20
CDK4 Inhibitor
ZDLD20 is a selective inhibitor of CDK4, exhibiting an IC50 value of 6.51 μM. This β-carboline compound demonstrates significant anti-cancer properties, particularly against HCT116 cells, by inhibiting colony formation, invasion, and migration. Additionally, ZDLD20 promotes apoptosis and induces G1 phase cell cycle arrest, making it a valuable tool for cancer research and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2762279-02-5 |
| Applications | CDK4 Inhibitor |
| Formula | C22H22N6O |
| Molecular Weight | 386.45 |
| SMILES | O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NC4=NC=C(N5CCN(C)CC5)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.