Zedoresertib

Catalog No.: A54131
WEE1 Inhibitor
Zedoresertib, a potent WEE1 inhibitor, exhibits an IC50 value of 0.8 nM and effectively inhibits phospho-CDC2. By abrogating the G2 checkpoint, Zedoresertib enhances the sensitivity of cancer cells to DNA-damaging agents, making it a valuable tool for anticancer research. This compound is essential for studies investigating cell cycle regulation and therapeutic strategies in oncology.
Grouped product items
Size Price Stock Qty
1mg
$75.00
In stock
5mg
$195.00
In stock
10mg
$265.00
In stock
25mg
$450.00
In stock
50mg
$625.00
In stock
100mg
$790.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZedoresertib, a potent WEE1 inhibitor, exhibits an IC50 value of 0.8 nM and effectively inhibits phospho-CDC2. By abrogating the G2 checkpoint, Zedoresertib enhances the sensitivity of cancer cells to DNA-damaging agents, making it a valuable tool for anticancer research. This compound is essential for studies investigating cell cycle regulation and therapeutic strategies in oncology.
Product Information
Catalog NumA54131
FormulaC26H28Cl2N6O
Molecular Weight511.45
CAS Number2243882-74-6
SMILESO=C1C2=CN=C(NC3=CC=C(C4CCN(CC4)C)C(C)=C3)N=C2N(CN1C5=C(Cl)C=CC=C5Cl)C
SynonymsDebio 0123; WEE1-IN-5
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2