Fig. 1 · Structure
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Zifaxaban
FXa Inhibitor
Zifaxaban is a selective and competitively acting Factor Xa (FXa) inhibitor, demonstrating an IC50 of 11.1 nM for human FXa. This compound exhibits over 10,000-fold selectivity against other serine proteases. It serves as a valuable tool for research on arterial and venous thrombosis, facilitating investigations into antithrombotic therapies and mechanisms of coagulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1378266-98-8 |
| Applications | FXa Inhibitor |
| Formula | C20H16ClN3O4S |
| Molecular Weight | 429.88 |
| SMILES | O=C(C1=CC=C(Cl)S1)NC[C@H]2CN(C3=CC=C(N4C=CC=CC4=O)C=C3)C(O2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.