Fig. 1 · Structure
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ZIKV-IN-2
MTase Inhibitor
ZIKV-IN-2 is a potent inhibitor of the Zika virus (ZIKV) NS5 methyl transferase (MTase), exhibiting an IC50 value of 38.86 μM. This compound effectively inhibits ZIKV replication and infection, making it a valuable tool for studying the pathogenicity and lifecycle of the Zika virus. ZIKV-IN-2 is suitable for applications in antiviral research and development focused on therapeutic strategies against Zika virus.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 910582-16-0 |
| Applications | MTase Inhibitor |
| Formula | C39H42O4 |
| Molecular Weight | 574.75 |
| SMILES | [H][C@]12CCC([C@H]([C@@]1(CC[C@H]([C@]2(COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C)O)C)/C=C/C6=CCOC6=O)=C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.