Fig. 1 · Structure
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ZIKV-IN-3
MTase Inhibitor
ZIKV-IN-3 is a potent inhibitor of Zika virus (ZIKV) NS5 methyl transferase (MTase), demonstrating an IC50 value of 18.34 μM. This compound effectively inhibits ZIKV replication and infection, making it a valuable tool for research into the Zika virus and its associated pathways. ZIKV-IN-3 can aid in the development of therapeutic strategies targeting ZIKV infection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 947699-46-9 |
| Applications | MTase Inhibitor |
| Formula | C39H41NO4 |
| Molecular Weight | 587.75 |
| SMILES | O=C1OCC=C1/C=C/[C@@H]2C(CC[C@]3([H])[C@@](COC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)(C)/C(CC[C@@]23C)=N/O)=C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.