Fig. 1 · Structure
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ZINC00640089
LCN2 Inhibitor
ZINC00640089 is a specific inhibitor of Lipocalin-2 (LCN2), a protein involved in various physiological processes. This compound has been shown to inhibit cell proliferation and viability while reducing AKT phosphorylation levels in SUM149 cells. ZINC00640089 presents significant potential for research applications in inflammatory breast cancer (IBC), contributing to the understanding of LCN2's role in tumor biology and therapeutic responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 667880-11-7 |
| Applications | LCN2 Inhibitor |
| Formula | C20H13F3N2O2 |
| Molecular Weight | 370.33 |
| SMILES | O=C(CN1C(C2=C3C1=CC=CC3=CC=C2)=O)NC4=C(C(F)(F)F)C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.