Fig. 1 · Structure
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ZINC05626394
Cytochrome P450 Inhibitor
ZINC05626394 is a selective inhibitor of cytochrome b5 reductase 3, which enhances nitric oxide bioavailability. This compound demonstrates potential anti-cancer properties, particularly when used in conjunction with antibody-drug conjugates (ADCs) and immune checkpoint inhibitors. Its efficacy may be influenced by various resistance mechanisms, such as antigen-related resistance and endocytosis limitations, making it an intriguing candidate for further investigation in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 189057-68-9 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C11H10N2OS2 |
| Molecular Weight | 250.34 |
| SMILES | O=C(N1)C=C(NC1=S)CSC2=CC=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.