Fig. 1 · Structure
Documents & Downloads
ZINC69391
Rac1-GEF Interaction Inhibitor
ZINC69391 is a selective Rac1-GEF interaction inhibitor that targets the Trp56 residue on the Rac1 surface. By disrupting the interaction between Rac1 and Dock180, ZINC69391 effectively lowers Rac1-GTP levels. This compound has demonstrated significant biological activity, inducing apoptosis and exhibiting antiproliferative and antimetastatic effects, making it a valuable tool for cancer research and studies investigating Rac1 signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 303094-67-9 |
| Applications | Rac1-GEF Interaction Inhibitor |
| Formula | C14H14F3N5 |
| Molecular Weight | 309.29 |
| Synonyms | N'-(4,6-dimethylpyrimidin-2-yl)-N-[2-(trifluoromethyl)phenyl]guanidine; CysHHC10 acetate(1408311-03-4 free base) |
| SMILES | N=C(NC1=CC=CC=C1C(F)(F)F)NC2=NC(C)=CC(C)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.