ZK 187638 is an AMPA receptor antagonist that effectively inhibits kainate-induced currents in cultured hippocampal neurons, demonstrating noncompetitive antagonism with an IC50 of 3.4 μM. This compound is valuable for research applications focused on synaptic transmission, neuroprotection, and the study of excitotoxicity in neurodegenerative disorders.
ZK 187638 is an AMPA receptor antagonist that effectively inhibits kainate-induced currents in cultured hippocampal neurons, demonstrating noncompetitive antagonism with an IC50 of 3.4 μM. This compound is valuable for research applications focused on synaptic transmission, neuroprotection, and the study of excitotoxicity in neurodegenerative disorders.
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