Fig. 1 · Structure

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ZK-93426

Benzodiazepine Receptor Antagonist

ZK-93426 is a benzodiazepine receptor antagonist that primarily targets the benzodiazepine site of the GABA-A receptor. This compound has been shown to induce generalized myoclonic jerks and tonic-clonic seizures without affecting motility in subjects. ZK-93426 serves as a valuable tool for investigating the mechanisms underlying withdrawal reactions in models of benzodiazepine dependence, facilitating research into addiction and pharmacological interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 89592-45-0
Applications Benzodiazepine Receptor Antagonist
Formula C18H20N2O3
Molecular Weight 312.36
SMILES
O=C(C1=C(C)C2=C(C=N1)NC3=C2C(OC(C)C)=CC=C3)OCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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