Fig. 1 · Structure
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ZL-Pin01
Pin1 Inhibitor
ZL-Pin01 is a potent covalent inhibitor of Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) that effectively disrupts Pin1-substrate interactions. With an IC50 value of 1.33 μM, ZL-Pin01 serves as a valuable tool for investigating the role of Pin1 in various biological processes. This compound is particularly useful in research focused on cellular signaling, protein folding, and disease mechanisms associated with Pin1 dysregulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1047464-92-5 |
| Applications | Pin1 Inhibitor |
| Formula | C14H17ClN2O3S |
| Molecular Weight | 328.81 |
| SMILES | O=C1CSC2(CCN(C(CCl)=O)CC2)N1CC3=CC=CO3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.