Signaling Pathway
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| Discription | ZL0420 is a potent and selective BRD4 inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2 respectively and good selectivity over that of the related BRD2 homolog. |
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| Catalog Num | A16829 |
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| Formula | C16H16N4O2 |
| Molecular Weight | 296.32 |
| CAS Number | 2229039-45-4 |
| SMILES | CC1=C(O)C=C(N)C(/N=N/C2=CC(CCC(N3)=O)=C3C=C2)=C1 |
| Synonyms | ZL 0420, ZL-0420 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 58 mg/mL (195.73 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.75 mL | 168.74 mL | 337.47 mL |
| 0.5 mM | 6.75 mL | 33.75 mL | 67.49 mL |
| 1 mM | 3.37 mL | 16.87 mL | 33.75 mL |
| 5 mM | 0.67 mL | 3.37 mL | 6.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
