Fig. 1 · Structure
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ZLD2218
Epigenetic Reader Domain
ZLD2218 is a potent inhibitor of the epigenetic reader domain BRD4, showing an IC50 value of 107 nM. This compound has demonstrated significant efficacy in ameliorating kidney injury and fibrosis in various studies. ZLD2218 serves as a valuable tool for researchers investigating the role of BRD4 in epigenetic regulation and its implications in kidney-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2713974-32-2 |
| Applications | Epigenetic Reader Domain |
| Formula | C22H18N4O |
| Molecular Weight | 354.40 |
| SMILES | O=C1C2=C(C(C3=CC4=C(C=CN4CC5=NC=CC=C5)C=C3)=CN1C)C=CN2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.