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ZLM-66

NNRTI

ZLM-66 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that demonstrates an IC50 of 41 nM against wild-type HIV-1 reverse transcriptase and an EC50 of 13 nM for wild-type HIV-1. As an analog of Doravirine, ZLM-66 is valuable for investigations into HIV replication and resistance mechanisms. This reagent is specifically designed for research applications related to AIDS and the evaluation of antiviral therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033486-43-7
Applications	NNRTI
Formula	C₂₄H₁₈F₃N₅O₃
Molecular Weight	481.43
SMILES	CN1C(CN(C=CC(C(F)(F)F)=C2OC3=CC(C#N)=CC(C4=CC(C)=CC=C4)=C3)C2=O)=NNC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.