Fig. 1 · Structure
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Zn(BQTC)
mtDNA/nDNA Inhibitor
Zn(BQTC) is a potent inhibitor of mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), causing significant damage to both genetic materials and subsequently disrupting mitochondrial and nuclear functions. This compound activates the DNA damage-induced apoptotic signaling pathway, demonstrating selective antiproliferative activity against A549R cells. Zn(BQTC) is valuable for research focused on cancer biology and the mechanisms underlying DNA damage response and apoptosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2785342-54-1 |
| Applications | mtDNA/nDNA Inhibitor |
| Formula | C30H39Cl2N5O3Zn |
| Molecular Weight | 653.95 |
| SMILES | O=C([N]12[Zn+2]([NH]3CC2)([NH]4CC3)[NH](CC4)CC1)CCCCCCOC5=C(OC6=CC=CC=C76)C7=NC8=CC=CC=C58.[Cl-].[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.