Documents & Downloads

ZNL-0056

ATP-competitive Inhibitor

ZNL-0056 is an orally active ATP-competitive inhibitor that targets the Cys797 and Cys775 residues in the ATP binding site of the epidermal growth factor receptor (EGFR). This compound selectively inhibits EGFR activity and its downstream signaling pathways in H3255 cells. ZNL-0056 is valuable for research focused on cancer therapy and the mechanisms of EGFR-related signaling in tumor progression.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2767987-38-0
Applications	ATP-competitive Inhibitor
Formula	C₂₅H₂₇N₅O₃S
Molecular Weight	477.58
SMILES	O=C(C1=CSC(NC(C=C)=O)=C1)NC2=NC3=CC=CC(C)=C3N2[C@H]4CN(CCCC4)C(C=C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.