ZNL-05-044 is a potent inhibitor of cyclin-dependent kinase 11 (CDK11), demonstrating IC50 values of 0.23 μM for CDK11A and 0.27 μM for CDK11B, as assessed using the NanoBRET assay. This compound induces G2/M cell cycle arrest and disrupts RNA splicing mechanisms. ZNL-05-044 is valuable for research applications focusing on cell cycle regulation and the role of CDK11 in RNA processing.
ZNL-05-044 is a potent inhibitor of cyclin-dependent kinase 11 (CDK11), demonstrating IC50 values of 0.23 μM for CDK11A and 0.27 μM for CDK11B, as assessed using the NanoBRET assay. This compound induces G2/M cell cycle arrest and disrupts RNA splicing mechanisms. ZNL-05-044 is valuable for research applications focusing on cell cycle regulation and the role of CDK11 in RNA processing.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: