Fig. 1 · Structure
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Zolasartan
Drug Derivative
Zolasartan is a drug derivative designed to selectively antagonize angiotensin II receptors, primarily targeting the AT1 receptor subtype. This compound exhibits potent vasodilatory effects, making it beneficial in the treatment of hypertension and heart failure. Additionally, Zolasartan's unique pharmacological profile renders it useful for investigating the role of the renin-angiotensin system in cardiovascular disease research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 145781-32-4 |
| Applications | Drug Derivative |
| Formula | C24H20BrClN6O3 |
| Molecular Weight | 555.81 |
| Synonyms | GR-117289 |
| SMILES | O=C(C1=C(Cl)N=C(CCCC)N1CC2=CC=C(OC(C3=CC=CC=C3C4=NN=NN4)=C5Br)C5=C2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.