Fig. 1 · Structure
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Zoledronic acid disodium tetrahydrate
Anti-resorptive Agant
Zoledronic acid disodium tetrahydrate is a third-generation bisphosphonate that primarily functions as an anti-resorptive agent. It effectively inhibits the differentiation and induces apoptosis in osteoclasts, leading to reduced bone resorption. Additionally, this compound exhibits anti-cancer properties, making it valuable for research in bone metabolism and oncology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 165800-07-7 |
| Applications | Anti-resorptive Agant |
| Formula | C5H18N2Na2O11P2 |
| Molecular Weight | 390.13 |
| Synonyms | Zoledronate disodium tetrahydrate; CGP 42446 disodium tetrahydrate; CGP42446A disodium tetrahydrate; ZOL 446 disodium tetrahydrate |
| SMILES | OC(P(O)(O)=O)(P(O)(O)=O)CN1C=CN=C1.[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Na].[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.